30 Jan '12, 1pm

Caffeine is just another Drug of Abuse

Caffeine is just another Drug of Abuse

A chemical is only as good as its receptor, and that receptor is only as good as where it’s located, where those neurons are going, and what they connect to. In this case, we know that 2A Adenosine receptors are very densely located in the basal ganglia, an area of the brain known for its role in things like locomotor activity, arousal (which may be awake, but may also mean alert to stimuli), and responses to rewarding stimuli such as drugs of abuse. So if caffeine and psychostimulants like cocaine work in the same brain areas, the basal ganglia, and both affect dopamine, why is one so much less addictive than the other?

Full article: http://shotzombies.com/2012/01/30/caffeine-is-just-anothe...

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